Non-Formulary Use Criteria: **1. Prescribed on a case-by-case basis only for inmates with a high risk of opioid overdose who are releasing from BOP custody or transferring to a residential reentry center or home confinement**2. Nasal dosage form is the preferred first-line therapy prior to auto-injector use.** **3. When naloxone nasal is prescribed, appropriate education on the risks and symptoms of opioid overdose and the use of naloxone must be provided to the inmate and documented in the medical record.**